The company called “New Medical Technologies”, in collaboration with the researchers from the Institute of Epidemiology and Microbiology of Uzbekistan (UzNIIEMIZ) developed unique know-how methods as well as a special installation where these methods were applied (see here https://www.zmescience.com/science/donor-blood-is-still-not-always-free-0534/).
The installation considers the disinfection of medical instruments, items, tools and surfaces. The problem is that many instruments used in cosmetology, surgery, dentistry and other spheres are not allowed to be processed in conditions of high temperatures or while using strong chemicals. Methylene blue as a photosensitizer (sterilizing agent) was wise solvation to the problem. It was applied in a special installation that uses the method of photodynamic disinfection, offered by the New Medical Technologies Company.
The method is spread in different medical spheres such as dentistry, oncology, gynecology, urology, ophthalmology. It is also helpful if one has diseases of the respiratory tract and throat, for the treatment of skin diseases as well as in the diagnosis of various diseases. It takes around an hour to inactivate the virus. The company offers devices working in different modes, containing chambers of various sizes. All of these give an opportunity to place a great number of items and tools. Sterilization units of the New Medical Technologies Company are safe for medical stuff as well as for the environment; The equipment may be highly advised for use in the medical sphere as well as in service industries. What is more important, it does not have any direct analogs.
There is also another aspect that is worth being considered. A new approach was suggested for detecting most dangerous viruses. All of these are caused by the fact that viruses possess lymphotropic properties, that is, the ability to permeate in the lymphocytes of a person’s body and remain there. These include viruses of hepatitis B, C and HIV, influenza virus, hemorrhagic fever (Ebola group), which have lymphotropic internals.
The director of New Medical Technologies Company, Ovik Mkrtchyan noted that when they had been testing their new scientific method of research at the Republican Blood Transfusion Center, they discovered that 18% of samples (let’s mention enzyme immunoassay and polymerase chain reaction) that had been taken earlier with the help of so-called classical but old-fashioned research methods were infected by viral particles. They came to an inarguable conclusion about the old methods. They are less effective which means that it is quite risky to transmit donated blood with a harmful illness from a donator to a receiver.
Mkrtchyan adds that the method they have developed for detecting and assessing the viability of lymphotropic viruses has no analogs in the modern world. Everything has also been done for the safety of the donation system, including patients. These know-how methods are not very sophisticated and they have a great advantage – one doesn’t have to buy specific equipment for practical use – the devices used in every diagnostic laboratory will do. Those who work in the laboratories may just use instructions for conducting the study so that they will easily be able to apply the new methods into practice with no need for taking special courses or additional consultations.
We are acquainted with the fact that almost everywhere hospitals are in great demand for blood donations, but at the same time, it is up to the donation system to persuade people that there are no harmful viral particles such as hepatitis and HIV are presented in the blood. Testing of antiviral medicine is critical to the safety of blood transfusion. Nevertheless, the most useful diagnostic methods to identify viruses may not usually precise; sometimes testing results finding viruses and determining their viability in donated blood, are untrustworthy.
Definite factors may influence such a low detection and they are the following ones:
– drawbacks of methods leading to mistakes in the results of the investigation;
– inability to recognize viruses at low viral load titers;
– impossibility for determining the harmfulness of viruses, that is, determining their viability;
– violation of the requirements during the study, including human factor, violation of the procedure, etc.
As a result a patient may get infected with viruses containing RNA and DNA (here it should be noted that COVID-19 is a virus containing RNA), bacteria, spores and fungi or blood-borne infections. The situation is turning into a dangerous one as WHO officials mark that in some countries there are no proper guarantees of high quality of these testing. We can definitely examine the statistics made by WHO. It shows that an alarming situation has been developed in some areas: violations of the protocol of research and blood tests were done and announced in 35 countries at the moment when donated blood had been gathered. WHO notes an evident difference between countries with different income.
Moreover, the situation becomes dramatically visible because of the lack of irregular medical supplies and tools, as well as highly professional working stuff. It may seem to benonsense that 43% of hospitals where blood transfusions are performed do not possess special systems for reporting adverse events of blood transfusion.
However, such experiments had already been taken in Japan and in some other countries, but they did not contribute a lot for the human society. It took a few years to invent the method of identification viruses in lymphocytes of blood donated by donors and at last it was claimed to be the first completed research in the field. A number of strategies developed by New Medical Technologies have recently been patented and used for excluding false negative results. For example, while testing donated blood for HBV and HCV and HIV CC as well as fixing the life expectancy of lymphotropic viruses; for detecting them in a biological matrix when the concentration of the virus is under the sensitivity limit of the polymerase chain reaction method.
Nevertheless, one may come to a conclusion that New Medical Technologies company is a real trailblazer with all the new methods and installations saving people’s health and probably it’s just the beginning of their scientific story.